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Scientist, Natural Product Discovery (60%-80%)
Entreprise:SpheroBiotics, Employeur direct
Contacter SpheroBiotics   |  Enregistrer cette offre  |  Toutes les offres de cet employeur
Description du poste↓Profil de l'employeur↓
Date de publication09.06.2020
Numéro de référencePas d'information
Domaine d'activité
Recherche/ Développement
Lieu de travail***CH Suisse/ Schweiz/ Switzerland***, 4058 Basel
Expérience professionnelle réquiseoui
Expérience professionnelleJunior Professional (1 à 3 ans d'experience)
Diplôme universitaireMaster
Brève descriptionNatural product expert for antibiotic R&D from microbiota.

Description complèteMicrobiology • Antimicrobial Testing • Fermentation • Product Characterization

Your responsibilities include:
• Effective contribution to SpheroBiotics’ efforts to discover, isolate, and characterize novel classes of antimicrobials
• Design and conduct high-throughput screening campaigns and secondary assays
• DNA isolation, metagenomic and whole-genome sequencing
• MIC assays using lab automation
• Develop and execute plans for cultivation and product fermentation with non-laboratory strains
• Develop and execute plans for small scale natural product purification
• Assist with the design of streamlined drug identification and de-replication strategies
• HPLC, MS/MS; (NMR optional)
• Chemical structure database query
• Biosynthetic gene cluster analysis (optional)

• PhD in natural product research or at least 2 years of relevant industry experience
• Microbiology techniques (bacteria and fungi)
• Experienced in next-generation sequencing techniques
• Experience with flow cytometry and/or microfluidics
• Extensive knowledge of natural product fermentation, purification, and identification
• Good knowledge in transfer of pilot fermentation to intermediate scale
• Experience in the antibiotic discovery sector a plus
• Highly motivated, solution-oriented, and a good team player
• Excited about mastering unforeseen challenges, meticulous, analytical, inventive, and reliable
• Must be eligible to work in Switzerland
Offre d'emploi (voir PDF ->)NaturalProductExpert_SpheroBiotics
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